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Infectiousness and antiretroviral therapy

A man transmitted HIV to his regular male partner despite taking antiretroviral treatment and having an undetectable viral load in his blood, German doctors report in the journal Antiviral Therapy. The authors believe that this is the first recorded instance of an individual with an undetectable viral load infecting a sexual partner with HIV.

In an editorial accompanying the case report, two of the authors of what has come to be known as the “Swiss Statement”, whilst acknowledging a “very low” risk of transmission from individuals taking antiretroviral therapy with an undetectable viral load, highlight what they believe to be some weaknesses in the documentation of this case. Furthermore, they point out that in their own experience “all suspected cases of transmission during antiretroviral therapy turned out to have another source.”

And a separately published study looks likely to further fuel the already fierce debate about the infectiousness (or otherwise) of patients being treated with antiretroviral drugs. French investigators report in the August 20th edition of AIDS that 5% of antiretroviral-treated men with an undetectable viral load in their blood had detectable HIV in their semen. None of these men had a sexually transmitted infection.

http://www.aidsmap.org/en/news/99DF7ED6-786E-4C29-B2D3-280ABB144C12.asp

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This information was retrieved from the Treataware website (www.treataware.info) on 19 Nov 2008. For further information, please consult the website or call the NAPWA office on 02 8568 0300.