About this trial
The aim of the study is to identify any changes in the HBV DNA that might be associated with resistance to tenofovir, to determine how long any changes take to occur and the effect of these changes on the clinical response to tenofovir.
Background information
HIV/HBV coinfection is not uncommon. 6-9% of people with HIV in developed countries also have chronic hepatitis B (HBV). HIV impacts on the natural progression of HBV infection in various ways. It can cause HBV to replicate faster and increase the risk of liver disease.
We know that tenofovir is active against both HIV and hepatitis B, but what we don't know is whether we can develop resistance to the drug and if so what this means to our health outcomes.
| Official title: | A surveillance program for the detection of hepatitis B virus (HBV) resistance to tenofovir (TDF) in HIV-HBV co-infected patients |
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| What is this trial studying? | Existing drug |
| How many participants will this trial enrol? | 92 The exact number of participants may be lower or slightly higher than this. Some trials also have specific quotas for participants from each state, city or clinic. |
| How long is this trial planned to go for? | Participants in this trial will be asked to take the trial drug for 2 years. |
| Who can enrol in this trial? | You may be eligible to participate in this trial if you meet the following criteria:
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| Links to further information: | |
| Related trials: | |
| Can I access this treatment other than by enrolling in this trial? | Tenofovir is a licensed s100 drug |
| Keywords: | coinfection, hepatitis B, tenofovir |
If you are interested in enrolling in this trial
Before making the decision to participate in any clinical trial, NAPWA recommends that you discuss the potential benefits and risks of participation with your treating doctor. Your doctor can also provide advice about your eligibility to participate in the trial.
- You can print this page to take it with you to the doctor – just use your browser's 'print' function.
- Before making the decision to participate in any clinical research, read our background information.
- Email NAPWA if you have any questions or comments about this trial
- Call the Treataware info line if you need further advice
This factsheet, produced by Positive Life NSW, provides you with information and some questions to ask if you are considering participating in a clinical trial.