Treataware

Trials where the study type is 'IMMUNE_BASED_TX'

ESPRIT (IL-2)

Fully enrolled | immune_based_tx | Last update: 8 Jul 2008
Entry status: 
randomised
open-label
Complete, approved
interleukin-2
immune-based therapies
cytokines
Keywords: 
interleukin-2
immune-based therapies
cytokines
Design keywords: 
randomised
open-label

This study compares people who are taking interleukin-2 (IL-2) along with their antiretrovirals with those who are not. The intention is to show whether or not the CD4 cells which are 'regained' after stimulating the immune system with IL-2 are actually good, functional CD4 cells capable of assisting in protecting against HIV-related immunodeficiency and AIDS.

STALWART: Interleukin-2 with and without antiretroviral therapy

No longer enrolling | immune_based_tx | Last update: 8 Jul 2008
Entry status: 
randomised
prospective
phase II
open-label
international
Complete, approved
interleukin-2
immune-based therapies
cytokines
Keywords: 
interleukin-2
immune-based therapies
cytokines
Design keywords: 
randomised
prospective
phase II
open-label
international

This study is looking at the effect that short cycles of interleukin-2 (IL-2) has on viral load and CD4 count when someone is taking antiretrovirals and when someone is not.

Interleukin-2 is a treatment which is administered by injection, twice a day, in treatment 'cycles' lasting for five days.

For the first period of the study, the period between cycles is 6-10 weeks. After that, when and how often people cycle is guided by their CD4 count.

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This information was retrieved from the Treataware website (www.treataware.info) on 3 Dec 2008. For further information, please consult the website or call the NAPWA office on 02 8568 0300.